Recasts headline, first paragraph, adds analyst quote, and updates prices with U.S. market open

By Chibuike Oguh

NEW YORK, Oct 22 (Reuters) -A gauge of global shares was lower on Tuesday, on track for the second consecutive day of losses, with U.S. yields higher as markets weighed uncertainty ahead of the U.S. election as well as the outlook on interest rate cuts.

Democratic Vice President Kamala Harris held a marginal 46% to 43% lead over Republican former President Donald Trump, according to a new Reuters/Ipsos poll, as both candidates vie to capture swing states ahead of Nov. 5.

The benchmark S&P 500 and the Dow were down, driven partly by losses in industrials, materials, and financial stocks. The Nasdaq was flat in choppy trading.

The Dow Jones Industrial Average .DJI fell 0.41% to 42,757.37, the S&P 500 .SPX fell 0.33% to 5,834.91 and the Nasdaq Composite .IXIC fell 0.07% to 18,526.02.

The pan-European STOXX 600 index .STOXX was also down 0.17%. MSCI's gauge of stocks across the globe .MIWD00000PUS fell 0.47% to 849.55.

"You have an election coming where both candidates are looking to spend more and it's not good for deficits," said Eric Beyrich, co-chief investment officer at Sound Income Strategies in New York. "It's also an environment where people don't expect the kind of interest rate cut as they did before."

The odds that the Fed will deliver a quarter-point cut at its Nov. 7 meeting are at 92%, while the chances of no rate cut is at 8%, according to CME's FedWatch tool. Benchmark 10-year Treasury yields US10YT=RR rose 0.2% bps to 4.184%.

Reporting Chibuike Oguh in New York; Editing by Alison Williams

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